Indications:
Cromolyn sodium, is effective in cases of bronchial asthma and has a preventive action when used before the development of bronchial asthma attack. Continuous long-term use of the product slowed and easy bouts of asthma, reduces the need for bronchodilatory drugs and corticosteroids. For relief of acute attacks of the product do not apply. Cromolyn sodium, is most effective in cases of a rather young age, who have not yet developed chronic changes in the lungs. Effect of the product is most pronounced in the atopic form of bronchial asthma, but the effect is also observed in infectious allergic form of the disease, and asthmatic bronchitis, pnevmoskleroze with attacks of breathlessness, especially if there is an allergic component.
Pharmacological Effects:
Cromolyn sodium, is the specific drugs used in asthma and bronhospasticheskih states. The basis of his actions is the ability to inhibit degranulation labrotsitov (mast cells), mucous membrane of respiratory tract and delay the release of these neurotransmitter substances that promote bronhiolospazma, allergy and inflammation (bradykinin, slow-reacting substance, histamine, etc.). Possible that the effect of the product is also linked in part to the blockade of receptors specific to inflammatory mediators, also holino and adrenomediatorov lymphoid cells. The properties of ordinary blockers H-receptor-cromolyn sodium is not.
The action of cromolyn sodium is clearly manifested in the local use by inhalation. At intake the effect does not develop.
Cromolyn sodium, Dosage and administration:
The drug used in powder form in capsules for inhalation. Spraying powder inhalation has produced with a special pocket turboingalyatora (Spingaler “), which placed a capsule with the product. When you click on the upper part (cover) inhaler capsule is punctured and the powder when inhaled enters the respiratory tract. To empty the capsule requires 4 energetic inspiration.
Inhalation produces every day. Begin with the application of 1 capsule 4 times daily at intervals of 4 – 6 hours in severe cases sometimes increase the dose up to 8 capsules per day (3 hours 1 capsule). After improving the number of inhalations is gradually reduced by choosing an effective maintenance dose.
Cromolyn sodium, can be used in conjunction with bronhorasshiryayuschimi drugs and corticosteroids. Dose corticosteroids can usually significantly reduce gradually, and in some cases completely stop using them.
The action of cromolyn sodium develops gradually. Full effect is usually 2 – 4 weeks from the start of treatment. Treatment should be prolonged. When you remove the product may resume attacks.
Cromolyn-sodium contraindications:
The drug should not appoint women in the first 3 months of pregnancy and children up to 5 years. Caution (reduced dosage) is required in cases with liver and kidney.
Cromolyn-sodium side effects:
If you are using cromolyn sodium sometimes have a cough and intermittent bronhiolospazm; cough calming reception glass of water immediately afterwards to inhalation, while in case of repeated bronhiolospazma make pre-inhalation bronhorasshiryayuschego funds (see Izadrin, ortsiprenalina sulfate).
Storage Conditions:
List B. Keep away from flames and heat sources.
Cromolyn-sodium composition:
Disodium 5, 5 – [(2-oksitrimetilen) dioxide bis (4-oxo)-4H-1-benzopyran-2-carboxylic acid], or 5, 5 – (2-Disodium oksitrimetilendioksi) bis (4-oxo )-4H-chromen-2-carboxylic acid.
Attention!
Before applying the medication, “Cromolyn sodium,” it is necessary to consult a doctor.
Instruction is provided solely for information with “Cromolyn-sodium.”
